1. A 6-month-old infant with fever requires antipyretic therapy. Which medication is CONTRAINDICATED in this age group due to risk of Reye's syndrome?

2. A patient with diabetes mellitus type 2 presents with random blood glucose of 320 mg/dL, serum bicarbonate 18 mEq/L, and moderate ketonuria. Which medication class should be temporarily discontinued?

3. An elderly patient taking multiple medications presents with confusion, dry mouth, blurred vision, and urinary retention. Which medication class is MOST likely responsible?

4. A patient with hypertension and chronic kidney disease (proteinuria 1.2 g/day) should receive which antihypertensive class as first-line therapy for renoprotection?

5. A patient receiving long-term prednisone 20 mg daily requires dental Extraction. What is the MOST appropriate perioperative management?

6. Which medication requires therapeutic drug monitoring with target trough Levels of 10–20 mcg/mL for seizure control?

7. A patient with heart failure (ejection fraction 30%) is currently taking Lisinopril, furosemide, and carvedilol. Which additional medication has been Shown to reduce mortality in this population?

8. A patient with newly diagnosed hypertension has a blood pressure of 158/96 mmHg. According to the ACC/AHA 2017 hypertension guideline, what is the target blood pressure for most adults?

9. Which laboratory parameter should be monitored within 3 months of initiating Statin therapy?

10. A patient with type 2 diabetes has HbA1c of 9.2% despite maximum Metformin dose. Which medication class provides cardiovascular mortality Benefit in patients with established atherosclerotic cardiovascular disease?

11. Which medication requires dose adjustment based on international normalized Ratio (INR) monitoring?

12. A patient with chronic obstructive pulmonary disease (COPD) exacerbation Requires bronchodilator therapy. Which combination provides complementary Mechanisms of action?

13. Which medication should be avoided in patients with glucose-6-phosphate Dehydrogenase (G6PD) deficiency due to risk of hemolytic anemia?

14. A patient with atrial fibrillation has a CHA2DS2-VASc score of 4. What is the Recommended antithrombotic strategy?

15. Which medication requires avoidance of grapefruit juice due to inhibition of Intestinal CYP3A4 leading to increased systemic exposure?

16. A patient with heart failure develops hyperkalemia (serum potassium 5.8 mEq/L) while taking lisinopril and spironolactone. Which intervention is MOST appropriate?

17. Which medication class is FIRST-LINE for treatment of acute uncomplicated Cystitis in non-pregnant women according to IDSA guidelines?

18. A patient with depression develops sexual dysfunction while taking sertraline. Which alternative antidepressant has the LOWEST risk of sexual side effects?

19. A prescription reads: "Amoxicillin 500 mg cap: Sig: 1 cap po tid x 10 days." How many capsules should be dispensed?

20. Which medication requires a "black box warning" label regarding risk of tendon rupture and should include patient counseling about immediate discontinuation with tendon pain?

21. A patient presents a prescription for codeine-containing cough syrup. According to Yemeni controlled substance regulations, what documentation is REQUIRED at dispensing?

22. Which medication requires refrigeration (2–8°C) after reconstitution and has a beyond-use date of 14 days?

23. A patient requests an emergency refill of levothyroxine without a valid prescription. What is the pharmacist's LEGAL obligation under Yemeni pharmacy law?

24. Which labeling element is REQUIRED on all dispensed prescription containers in Yemen?

25. A prescription for warfarin includes "INR monitoring weekly until therapeutic." What is the pharmacist's professional responsibility?

26. Which medication requires auxiliary labeling stating "Avoid prolonged sun exposure" due to photosensitivity risk?